Active Ingredients in Provillus. Provillus uses a combination of natural substances that are essential for good health and hair growth. Vitamin B6 is an integral element for 100 enzymes that contribute to protein and red blood cell metabolism. Biotin, part of the vitamin B complex, is a supplement that provides nutrition for both your hair and scalp. Provillus also makes use of zinc, nettle root, pumpkin oil extract, saw palmetto, and several other naturally occurring substances to break down DHT and to stimulate new hair growth.